Microsoft Word (DOC, DOT, DOCX, and DOCM files), Microsoft Excel (XLS files, and XLSX and XLSM files), Microsoft PowerPoint (PPT and PPS files as well as PPTX, PPSX, and PPTM files), Rich Text Format1 (RTF files), text files (TXT files), TeX (TEX files), HTML, XHTML, XML, SGML, Adobe FrameMaker (in MIF format), Adobe InDesign (IDML files, in INX exchange format) Adobe InCopy (INCX format), BroadVision QuickSilver (ILDOC files), QuarkXPress (export to XTG format, re-import upon translation), Executable files (EXE files) Dynamic Link Library (DLL files), Resource Script files (RC, RC2, and DLL files). The list below includes only some of the existing available software and website platforms.

According to a 2006 survey undertaken by Imperial College of 874 translation professionals from 54 countries, primary tool usage was reported as follows: Trados (35%), Wordfast (17%), Déjà Vu (16%), SDL Trados 2006 (15%), SDLX (4%), STAR Transit fr (3%), OmegaT (3%), others (7%). A number of computer-assisted translation software and websites exists for various platforms and access types.

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